Angiopoietins 1−4 (Ang1−4) represent an important family of growth factors, whose activities are mediated through the tyrosine kinase receptors, Tie1 and Tie2.The best characterized are angiopoietin-1 (Ang1) and angiopoietin-2 (Ang2).Ang1 is a potent angiogenic growth factor signaling through Tie2, whereas Ang2 was initially identified

Abstract In German Martingale this volume of Artifact, we wish to explore design through the design concept, and thereby the societal praxis of designers through the theoretical concept of design.Design is praxis, but it is also formed by the way we frame the concept of design.We have endeavoured to give space for a rather broad range of contributo

One of the most important and famous historical documents from the English legal and constitutional legacy is the Magna Carta Libertatum.Signed and sealed in the year 1215 the Magna Carta is further on viewed as the sole inception of the idea of limiting the power of the ruler trough legal WASH BRUSH rules.That limitation is to be made with legal r

The activity time of the lesser bamboo bat, Tylonycteris pachypus (Temminck, 1840), was investigated at two observation locations in southern China: Longzhou and Guiping.Two bouts of activity (post dusk and predawn), with an intervening period of night roosting at diurnal roosts, were identified.The period of activity within each bout was usually l

Abstract Background Several studies considered the relation between long-term exposure to particulate matter (PM) and total mortality, as well as mortality from cardiovascular and respiratory diseases.Our aim was to provide a comprehensive review of European epidemiological studies on the issue.Methods We searched the Medline database for epidemiol